22nd Century Group, Inc. is an agricultural biotechnology company that aims to reduce tobacco harm, enhance health and wellness through plant science for multiple industries. They produce low nicotine content tobacco products and research cigarettes named VLN King, VLN Menthol King and SPECTRUM respectively. The company is headquartered in Buffalo, New York, and collaborates with Keygene N.V. to develop hemp/cannabis plants for various medical and agricultural uses.