Vertex Pharmaceuticals develops and sells treatments for cystic fibrosis, including SYMDEKO/SYMKEVI, ORKAMBI, KALYDECO, and TRIKAFTA, which are specifically designed for patients with certain mutations. The company has several drugs in clinical trials for the treatment of kidney disease, diabetes, and pain management. Vertex mostly sells its products to specialty pharmacies and distributors in the United States, as well as internationally.